動物を用いた循環機能検査、生体材料評価
メンバー： 田中綾、福島隆治
分野： 材料工学、実験動物学、動物生命科学、薬学、内科系臨床医学、外科系臨床医学
所属： 農学研究院
キーワード： 循環器作動薬、人工血管、テレメトリー、心臓CT、コンダクタンスカテーテル、心臓エコー
ウェブサイト：
研究概要
当研究室では人工血管、癒着防止膜、パッチグラフトといった医用材料の評価、カルシウムセンシタイザーや利尿薬などの循環器作動薬の評価等を行っています。心エコーや心臓CTなどの一般的な心臓検査に加え、IVUSやコンダクタンスカテーテル、2DTT、VFM、テレメトリーなどによる評価も可能です。
主要論文・参考事項
1. Hamabe L, Fukushima R, Kawamura K, Shinoda Y, Che HH, Suzuki S, Aytemiz D, Iwasaki T and Tanaka R. Evaluation of changes in left ventricular myocardial function observed in canine myocardial dysfunction models using two-dimensional tissue tracking technique. Journal of veterinary science. 2013.
2. Aytemiz D, Suzuki Y, Shindo T, Saotome T, Tanaka R and T. A. In vitro and in vivo Evaluation of Hemocompatibility of Silk Fibroin Based Artificial Vascular Grafts. International Journal of Chemistry. 2014;6.
3. Suzuki S, Fukushima R, Ishikawa T, Hamabe L, Aytemiz D, Huai-Che H, Nakao S, Machida N and Tanaka R. The effect of pimobendan on left atrial pressure in dogs with mitral valve regurgitation. J Vet Intern Med. 2011;25:1328-33.
4. Hsu H, Dozen M, Matsuno N, Obara H, Tanaka R and Enosawa S. Experimental nonalcoholic steatohepatitis induced by neonatal streptozotocin injection and a high-fat diet in rats. Cell medicine. 2013;6:57-62.
お問い合わせ先
東京農工大学・先端産学連携研究推進センター
urac[at]ml.tuat.ac.jp（[at]を@に変換してください）
circulatory function test and biomaterial accessment in animals
Research members： Dr. Ryo Tanaka, Dr. Ryuji Fukushima
Research fields： Material engineering, Laboratory animal science, Animal life science, Pharmacy, Clinical internal medicine, Clinical surgery
Departments： Institute of Agriculture
Keywords： 循環器作動薬,人工血管,テレメトリー,心臓CT,コンダクタンスカテーテル,心臓エコー
Web site：
Summary
In our laboratory, assessment of biomedical materials, such as artificial vessel, postoperative adhesion prevention sheet, and patch graft for cardiac surgery is provided. Also, the effects of cardiovascular drugs such as calcium sensitizer, diuretics and so on. In addition to ordinary cardiac devices such as cardiac echo and cardiac CT scan, specific devices such as IVUS, conductance catheter, 2DTT, VFM and telemetry system are available.
Reference articles and patents
1. Hamabe L, Fukushima R, Kawamura K, Shinoda Y, Che HH, Suzuki S, Aytemiz D, Iwasaki T and Tanaka R. Evaluation of changes in left ventricular myocardial function observed in canine myocardial dysfunction models using two-dimensional tissue tracking technique. Journal of veterinary science. 2013.
2. Aytemiz D, Suzuki Y, Shindo T, Saotome T, Tanaka R and T. A. In vitro and in vivo Evaluation of Hemocompatibility of Silk Fibroin Based Artificial Vascular Grafts. International Journal of Chemistry. 2014;6.
3. Suzuki S, Fukushima R, Ishikawa T, Hamabe L, Aytemiz D, Huai-Che H, Nakao S, Machida N and Tanaka R. The effect of pimobendan on left atrial pressure in dogs with mitral valve regurgitation. J Vet Intern Med. 2011;25:1328-33.
4. Hsu H, Dozen M, Matsuno N, Obara H, Tanaka R and Enosawa S. Experimental nonalcoholic steatohepatitis induced by neonatal streptozotocin injection and a high-fat diet in rats. Cell medicine. 2013;6:57-62.
Contact
University Research Administration Center(URAC),
Tokyo University of Agriculture andTechnology
urac[at]ml.tuat.ac.jp
(Please replace [at] with @.)