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Researches on analysis of light scattering phenomena and their applications to optical measurement systems in biomedical, physicochemical, and environmental research fields

Scene in an experiment

Research members: Dr. Toshiaki Iwai

Research fields: Electrical and electronic engineering, Applied physics, Biomedical engineering

Departments: Institute of Engineering

Keywords: light scattering, multiple scattering, Mie scattering generalized Lorentz-Mie theory, dynamic light scattering, optical coherence tomography, environmental particle, radiation pressure, optical tweezers, low-coherence dynamic light scattering

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Summary

Light scattering phenomena occur when objects to be measured are under illumination of light. Since the light propagating through a biological tissue or a dense suspension of particles is scattered many times, the multiple scattering becomes dominant. Based on analysis of such the multiple-scattering phenomena, the measurement systems have been studied in our laboratory to perform tomographic imaging of skin and biological tissues by optical coherence tomography; to manipulate and arrange nanoparticles or living cells by holographic optical tweezers; to characterize micro- and nano-particles in the dense media and Brownian dynamics in the area close to the interface between different phases by low-coherence dynamic light scattering; to image blood-vessel dynamics by diffusing light topography; and to develop optical counters for pollens and environmental particles.

Reference articles and patents

1) “Direct observation of submicron Brownian particles at a solid-liquid interface by extremely short coherence dynamic light scattering,” T. Watarai and T. Iwai, Appl. Phys. Express, 7 (2014) 10.7567/APEX.7.032502.

2) “Spectroscopic study on appearances of make-up skins using a visible RGB-LED OCT,” T. Tsugita, R. Kimura, and T. Iwai, Skin.Res. Technol. 20 (2014) 10.1111/srt.12130.

3)「光多重散乱現象解析」,岩井俊昭,光散乱の基礎と応用(講談社サイエンティフィック,東京,2014),第3章pp.109-134.

4) “Polarization analysis of light scattered by pollen grains of Cryptomeria japonica,” T. Iwai, Jpn. J. Appl. Phys. 52 (2013) 10.7567/JJAP.52.062404.

5) ”On-demand holographic optical tweezers,” J. Yamamoto and T. Iwai, Optical Nano and Micro Actuator Technology G. K. Knopf and Y. Otani (ed.) (CRC Press, Baca Raton, 2013) Chap.11, pp.333-345.

6) “Highly controllable optical tweezers using dynamic electronic holograms,” J. Yamamoto and T. Iwai, Curr. Pharm. Biotech., 13 (2012) 2655.

Contact

University Research Administration Center(URAC),
Tokyo University of Agriculture andTechnology
urac[at]ml.tuat.ac.jp
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